How a non-invasive biomarker could help with earlier breast cancer metastatic diagnosis?
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Every fourteen seconds, a woman gets a breast cancer diagnosis somewhere in the world. Although treatments for early-stage and non-metastatic breast cancer are now possible thanks to medical advances, advanced stage and metastatic breast cancer is thought to be incurable and has a very poor prognosis. Because early identification of breast cancer metastasis is crucial to the condition's therapy, a group of researchers has identified a non-invasive biomarker that may facilitate an earlier diagnosis. From the EVs of several metastatic breast cancer cell lines, a collection of protein expression profiles are gathered using an ultra-sensitive protein identification technique. They found that integrins v and 1 were persistently overexpressed in EVs with a strong metastatic background, among many other potential proteins. Fundamental understandings of the underlying processes of breast cancer metastasis have emerged as a result of the work. In addition to being clinically applicable...