How does Ultrasound imaging can help solve the Alzheimer's disease?

 Understanding the relationship between Alzheimer's disease and the brain's vascular system, with its complex network of vessels and veins, has long been a scientific challenge. Microvascular changes and Alzheimer's disease are interconnected. However, the precise mechanism, particularly the direction of the relationship between microvascular pathology and Alzheimer's disease pathology, is still unknown. By measuring how small contrast-agent microbubbles travel through the bloodstream, ultrasound microscopy provides quick and accurate images of animal microvasculature. Because microbubbles are easier to image and track with ultrasound, they are a useful imaging technique.



This ultrasound technology enables imaging of the entire brain at a resolution high enough to resolve micro vessels. The imaging system is inexpensive, portable, and widely available. If our method gains traction, we believe it will be quickly adopted by the Alzheimer's disease community. This level of imaging penetration and resolution is unprecedented.

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